Nitrofurantoin‐induced acute pulmonary toxicity
نویسندگان
چکیده
We report a case of a female admitted to the emergency department with fever and severe type I acute respiratory failure. After detailed examination, all other potential causes were excluded and the patient was diagnosed with nitrofurantoin-induced acute pulmonary toxicity.
منابع مشابه
Fatal Nitrofurantoin-Induced Pulmonary Toxicity: A Potentially Preventable Medical Error
The majority of patients affected with nitrofurantoin pulmonary toxicity are elderly women [1]. The proposed mechanism of toxicity is either idiosyncratic oxydant-mediated tissue injury by nitrofurantoin metabolites causing depletion of cellular glutathione (chronic form) or by immunological response induced by nitrofurantoin metabolites acting as heptanes and resulting a hypersensitivity react...
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